Serveur d'exploration sur la maladie de Parkinson

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Parkinson's disease and weight loss: A study with anthropometric and nutritional assessment

Identifieur interne : 000290 ( France/Analysis ); précédent : 000289; suivant : 000291

Parkinson's disease and weight loss: A study with anthropometric and nutritional assessment

Auteurs : Geneviève Durrieu [France] ; Marie-Elise Llau [France] ; Olivier Rascol [France] ; Jean-Michel Senard [France] ; André Rascol [France] ; Jean-Louis Montastruc [France]

Source :

RBID : ISTEX:6C5671AC5E8600AC3C536D68AEB1836D61F9A969

Abstract

Abstract: In order to investigate a putative weight loss in patients with Parkinson's disease, an anthropometric and biochemical study was undertaken. We compared body weight and indexes of fat [body mass index (BMI), tricipital skinfold] and lean [midarm muscle area (MMA), calf circumference] mass in men and women suffering from idiopathic Parkinson's disease with normal controls. We found that women suffering from Parkinson's disease exhibited a significant weight loss (−8.5%) and decreased calf circumference when compared with controls. A decrease (−4.3%) in total body weight was also found in men with Parkinson's disease but the difference did not reach the level of significance. Protein biochemical markers of nutritional status (albumin, prealbumin, retinol binding protein, transferrin) were normal in Parkinson's disease patients. The present study demonstrates the occurrence of weight loss in a large population of patients with Parkinson's disease. The putative mechanisms involved in the weight loss are discussed.

Url:
DOI: 10.1007/BF01818955


Affiliations:


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ISTEX:6C5671AC5E8600AC3C536D68AEB1836D61F9A969

Le document en format XML

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   |texte=   Parkinson's disease and weight loss: A study with anthropometric and nutritional assessment
}}

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